<p>Ophthalmic preparations are subject to microbiological contamination. Ophthalmic solutions used both for diagnostic and therapeutic purposes have found to be contaminated by pathogenic bacteria with reported rates as high as 70%, combined with severe ocular infections such as keratitis and endophthalmitis.</p>
<p>Unit-dose is one of the preservative-free eye solution. This is very effective in reducing the risk of inuse and cross-contamination. However, it is best adapted to treatment over a short period of time, and is questionable from an environmental point of view, especially regarding the overall emission of carbonfootprint throughout the product life cycle as well as the tremendous volume of waste generated.</p>